Indian Medicinal Plants: Uses and Propagation Aspects offers a unique compendium of more than 270 medicinal plant species from India with detailed taxonomic classifications based on the Bentham and Hooker system of classification. This study used 5 treatment groups, 0.9% NaCl as negative control and 0.25% pirantel pamoate as positive control and 60%, 80% and 100%. Until the last decade, it came to be a starting point for the lead discovery. Tea and Anting-anting leaves are suspected to contain tannin, a compound that can act as an antibiotic. Ethnopharmacological relevance: In antibacterial study all extract showed good inhibition zone against only three organisms i.e. The purpose of this study was to determine the effect of giving Anting-anting leaf extract (Acalypha indica L) as an anthelmintic to the time of death of pork roundworms (Ascaris suum Goeze). Patients and methods: The results showed that the fastest mortality rate of S. Scabiei was group p3 at 4.6 mites/hour., then P0, P2, P1 and PN respectively 3.5, 3.1, 1.9, and 1.3 mites/ hour. It has been reported to be useful in treating pneumonia, asthma, rheumatism and the decoction of of the mice against seizures and significantly (* = p<0.0001, ** =p<0.002) 2013-03-11T06:22:56Z Discussion: As well as being exploited for medicinal use, the roots of this plant are known to elicit a drug-like effect in cats. Acalypha indica leaves are used in the traditional medicine of India as a … The study aims to examine the Daboia russelli venom neutralization potential of the various leaf extracts of Acalypha indica (Euphorbiaceae) by in vitro and in vivo antisnake venom studies. Early symptoms occurred within 24 hours of the last ingested dose. The collected data demonstrate that Sudanese medicinal plants have been reported to possess a wide range of traditional medicinal uses including different microbial infections, gastrointestinal disorders, malaria, diabetes, rheumatic pain, respiratory system disorders, jaundice, urinary system inflammations, wounds, cancer, and different microbial infections. The data clearly indicated that the hydro-alcoholic crude extract and their hexane, ethyl acetate and methanol fractions of Acalypha indica showed good antioxidant and antibacterial activity. We report a case series in which acute hemolysis and methemoglobinemia after Acalypha indica ingestion were observed. Acalypha sanderi; Phonetic Spelling ack-ah-LY-phah HIS-pid-ah Description. Seven out of eight patients were diagnosed as methemoglobinemia. The research shows that leaf tea and anting-anting extraction have potential to be developed as an antibiotic. families, and the medicinal uses (among the tribes in the collection areas) of the plants. 3. Hutch. It follows then, that in addition to using medicinal herbs, many of which have proven efficacious by numerous studies [13][14][15][16][17][18]. For the traditional practices, the authors also mentioned several benefits of consuming the raw plant and decoction. 45.5±2.33, 32.8±1.62 respectively. Bhumi amla is acircum-tropical weed that look like amla. 2013-03-11T06:22:52Z The combination of herbs extract showed synergistic interaction towards stimulation of NO production. Isolation and identification of bacterial isolates by using standared biochemical tests. Abstract - Salmonella typhi is a bacteria that caused typhus disease . A total of 23 ethnomedicinal uses of E. goetzei are documented in this study from 62.5% of the countries where the species is indigenous. }, author={Nor Syahiran Zahidin and Syafiqah Saidin and Razauden Mohamed Zulkifli and … In conclusion, anting-anting (Acalypha indica L.) leaf extract has mortality rate against S. Scabiei var. According to ethno-medicinal uses, it is used for treating pneumonia, jaundice, piles, asthma, rheumatism, bedsores, wounds and skin disorders. Bacillus megaterium, Staphylococcus epidermidis, Pseudomonas aeruginosa, Priteus mirabilis, Klebsiella pneumonia, Salmonella typhimurium, Enterobacter aerogenes, Escherichia coli, Enterobacter cloacae. improving drug delivery system for better control and efficiency, Tithonia diversifolia is a shrub-like perennial or annual invasive plant, native to north and Central America. 1. As well as being exploited for medicinal use, the roots of this plant are known to elicit a drug-like effect in cats. Almost every part of the plant including the leaves, stem and roots are used as traditional remedies to treat and manage a panoply of ailments. application/pdf Pengobatan dengan menerapkan kearifan lokal merupakan salah satu alternatif dalam upaya penyembuhan. Methods Molecular docking Sublethal (50 mg/mL) and subinhibitory (25 mg/mL) doses of AI-M produced the optimal black pigmentation reduction to demelanise A. niger. Previous studies have also reported that both A. indica and C. asiatica have potent healing abilities (Shukla et al., 1999b; ... Our data are comparable with those from a previous study by. Acalypha indica is a herb that grows throughout the tropical regions of the world. In contrast, they demonstrated antagonism towards antifungal-demelanising properties. Chandra Mohan S, et al. Ethnopharmacological relevance: Acalypha is the fourth largest genus of the Euphorbiaceae family with approximately 450-570 species. In light of its long traditional use and the modern phytochemical and pharmacological evaluations summarized in this study, E. goetzei has been demonstrated to show a strong potential for therapeutic and health-maintaining uses. In poor communities, traditional medicine has remained as the most reasonable source of treatment of several diseases and microbial infections. Thus, the current article presents highlights from the published literature on plants as sources of anti-inflammatory agents. glidescore, Docking. Download DRUG LABEL INFO: PDF XML; Official Label (Printer Friendly) View All Sections Close All Sections. Preliminary studies on Acalypha Indica: proximate analysis and phytochemical screening, Inter J Pharmacy and Pharmaceutical Sciences. The effects of plant extracts on bacteria have been studied by a very large number of researchers in different part of the world. endstream In vitro HRBC membrane stabilization properties of these extracts at concentrations ranging from 2-400 μg/ml revealed inhibition of haemolysis induced by Russell's viper venom, in a concentration dependent manner. Further studies are crucial to validate these findings. Synthesis of standards confirmed the stereochemistry of both compounds emitted by the plant. [45] evaluated the antibacterial inhibition against fungal pathogens when compared to potentiality of ethanol and ethyl acetate solvent extracts Acalypha indica. scores order for all molecules reflected the experimental GABA agonists. A literature search revealed that C. macowanii has a lot of potential as a possible source of pharmaceutical products for the treatment of a wide range of human and animal diseases and ailments. The curation using chemical drugs may cause bacterial resistance if the treatment is not complete, especially when the system of the body decreases. Acalyphin is used as a substitute for ipecacuanha, a vermifuge, expectorant and emetic. E. goetzei has been widely used as a source of herbal medicine for several years without any adverse effects. (2003) carried out a non-comparative study to evaluate the safety and efficiency of Acalypha wilkesiana ointment using 32 Nigerians with mycological as well as clinical evidence of mycoses. Direct relationships between providers, and at a health systems level are crucial to successful collaboration, but the nature and extent of these relationships have yet to be adequately explored. development of Electrocardiography electrodes and circuit on wearable platform. Acalypha wilkesiana ointment is used to treat fungal skin diseases. A review of the literature was undertaken and an in-depth analysis of previous research on ethnobotany, therapeutic value, phytochemistry and pharmacology of C. macowanii throughout its distributional range in east, central and southern Africa. <> Multiple classes of phytochemicals including phenolic compounds, coumarins, flavonoids, saponins, stilbenoids, tannins and triterpenoids have been identified from E. goetzei bark, leaves and roots in different investigations. This review provides a basis for future investigation such as isolation of bioactive components and mechanism of action of the bioactivities elicited by this plant. Several pharmacological properties exhibited certain potentials based on the obtained results that came from different related studies. The data was collected from online journals, magazines, and books, all of which were published in English, Malay and Indonesian. Preliminary phytochemical analysis & Quantification of Total Phenols, In-vitro Antioxidant and Antibacterial activities of the hydro alcoholic (70% ethanol) extract of Acalypha indica and it's different fractions (Hexane, Ethyl acetate, methanol) were carried out against nine selected pathogenic bacteria. A laxative. leaves that are very commonly found growing wild on roadside, grass fields and on mountain slopes (9) . Acalypha indica L. ( A. indica) (family: Euphorbiaceae) is an annual herbaceous weed and widely distributed throughout the tropical region of India. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a description of the experimental procedure, a critical assessment of the results and their pharmacological and clinical relevance, and pertinent references. Acalypha indica var. Some of the alkaloids isolated from C. macowanii have demonstrated various biological activities when investigated in in vitro assays. The subjects of the study were Ascaris suum. There have been increasing calls for collaboration between Indigenous health practitioners (IHPs) and allopathic health practitioners (AHPs) in Africa. Acalypha ciliata Benth. That are showed by clear zone as indicate inhibition Salmonella typhi when tested antibacterial. Acalypha indica in the Germplasm Resources Information Network (GRIN), U.S. Department of Agriculture Agricultural Research Service. Acalypha ciliata Wall. Key words: Acalypha indica, Anti-epileptic, Anti-anxiolytic, GABA, Methodology and results: The stimulatory, antioxidant, and antibacterial activities of aqueous (A) and methanol (M) extracts of all the three vegetables were assessed alone and in combination in normal human dermal fibroblast (NHDF) cells in vitro. © 2008-2021 ResearchGate GmbH. This review was performed through a systematic search related to Acalypha indica including the ethnomedicinal practices, phytochemistry and pharmacological studies around the world. Literature sources included papers published in international journals, reports from international, regional and national organizations, conference papers, books, theses, websites and other grey literature. Treatment with traditional medicine is one of alternative way for curing typhoid fever. These findings help in the selection of herbs combination for potential natural drug discovery. Leaf extract obtained by boiling and drying. Aims: The oriental-based herbs Acalypha indica (AI), Centella asiatica (CA), and Sesbania grandiflora (SG) possess a broad range of undisclosed therapeutic activities which are edible and easily available throughout the year. Eight patients were included, mostly male with a median age of 61.5 years. At 500 µg/mL, CA-A and the combination CA-A+SG-A successfully induced RAW264.7 cells to produce NO at 17.85 µM and 40.84 µM, respectively. Conclusion, significance and impact of study: The combination of herb extracts showed better stimulation of NO production while the single herb extracts demonstrated good antifungal-demelanising activity. The plant is widely used in several countries such as Costa Rica, Democratic Republic of Congo, Kenya, Nigeria, Mexico, the Philippines, São Tomé and Príncipe, Taiwan, Uganda, and Venezuela to traditionally treat numerous diseases including diabetes, malaria, snake bite, measles, gastric, Elephantorrhiza goetzei (E. goetzei) commonly known as Goetze’s elephantorrhiza, is traditionally used as a decoction in the treatment of a variety of conditions such as pain, sores, sexually transmitted infections (STIs), gastro-intestinal disorders, microbial infections and genito-urinary system disorders. The power struggle which defines the relationship between IHPs and AHPs in Africa is a hindrance to their collaboration and as such could partly account for the limited success of efforts to foster collaboration to date. Cuniculi of 3.1 mites/hour, lethal concentration of 12.5% and potential as anti-scabies in vitro. ACALYPHA Indica 30C Homeopathic Remedy in 10 Gram by Urenus. Based on literature studies, Acalypha indica has the capability to serve as anthelmintic, anti-inflammation, anti-bacterial, anti-cancer, anti-diabetes, anti-hyperlipidemic, anti-obesity, anti-venom, hepatoprotective, hypoxia, and wound healing medicine. In INH induced convulsions MEAI The average time of Ascaris suum worm death at a concentration of a concentration of 60% for 228.5 minutes, a concentration of 80% for 174 minutes, and a concentration of 100% for 92 minutes. endobj It has numerous medicinal uses in India and is listed in the Pharmacopoeia of India as an expectorant to treat asthma and pneumonia. All rights reserved. for total phenolic content, Gallic acid was taken as a standard and the ethyl acetate fraction contains rich phenolic content than other fractions and the Ethyl Acetate fraction showed more DPPH radical scavenging activity. The method in this study was pre-experimental with a post test only group design. stream The neutralizing potency of different leaf extracts viz., petroleum ether, benzene, chloroform and acetone extracts of Acalypha indica prepared by successive solvent extraction at intraperitoneal dose levels of 250, 500 and 750 mg/kg revealed that the acetone extract possessed the most significant activity on venom-induced lethality. The plants that make up the Euphorbiaceae family, such as the species Euphorbiaceae acalypha hispida Burm. This paper reviews the ethnomedicinal importance of T. diversifolia, as well as its proximate analysis, phytochemistry, biological activities, and potential toxicity. history of applications among the different ethnic groups. 100 0 obj Crinum macowanii is used traditionally as a remedy for boils, diarrhoea, fever, inflammation, respiratory system problems, skin rashes, tuberculosis, wounds and urinary tract problems. P Acalypha indica (Euphorbiaceae) Chemical Part All parts ... Low PM High StdDev Reference 1-INOSITOLMONOMETHYLETHER ... ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. ... Acalypha indica is composed of various phytochemicals (Table 3) and nutrients which most of them play a role in human therapeutic property. In this study, we investigated the volatile components emitted by the plant roots and identified two iridoid compounds, (4R,4aR,7S,7aR)-isodihydronepetalactone and (4R,4aS,7S,7aR)-isoiridomyrmecin, which are known to affect behavioural activity in cats. Several Acalypha species are used as medicinal plants in Africa and in the Mascarene Islands. Methods: The 101 0 obj Aims: Acalypha indica (AI), Centella asiatica (CA), and Sesbania grandiflora (SG) are vegetables commonly used in traditional medicine in Asian countries to treat skin problems. Tujuan dari penelitian ini adalah memperoleh informasi efektifitas ekstrak daun teh dan daun anting-anting sebagai antibak t eri alami, khususnya S. typhi Penelitian dilakukan pada bulan Maret hingga Oktober 2012 di Labo r atorium Mikrobiologi Universitas Al Azhar Indonesia. So it can be concluded that the leaf extract of Acalypha L has an anthelmintic effect on the Ascaris suum worm. 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